U-Blot® RGS7 Polyclonal Antibody

Name: U-Blot® RGS7 Polyclonal Antibody
SKU: WP14277
Availability: InStock

$268.00

Size:50μL

SKU: WP14277-50

Catalog No.: WP14277

Specification: 50μL/100μL

Stock: In stock

U-Blot® RGS7 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：function:Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(o)-alpha is specifically enhanced by the RGS6/GNG5 dimer. May play a role in synaptic vesicle exocytosis. May play important role in the rapid regulation of neuronal excitability and the cellular responses to short-lived stimulations.,PTM:Palmitoylated.,PTM:Phosphorylation and subsequent interaction with 14-3-3 proteins inhibits GAP activity.,similarity:Contains 1 DEP domain.,similarity:Contains 1 G protein gamma domain.,similarity:Contains 1 RGS domain.,subunit:Heterodimer with GNG5. Interacts with RGS7BP, leading to regulate the subcellular location of the heterodimer formed with Gbeta5 (By similarity). Interacts with 14-3-3 protein Tau and SNAP25BP.,

Product Overview

Catalog No.: WP14277
SKU: WP14277-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: RGS7
Reactivity: Human,Mouse,Rat
Application: WB,ELISA,IHC
MW(Calculated): --
MW(Observed): 65kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human RGS7. AA range:155-204
Sequence: --
Specificity: RGS7 Polyclonal Antibody detects endogenous levels of RGS7 protein.
Gene Name: RGS7
Protein Name: Regulator of G-protein signaling 7
Other Name: RGS7;Regulator of G-protein signaling 7;RGS7
Organism-1: Human
Gene ID-1: 6000
SwissProt-1: P49802
Organism-2: Mouse
Gene ID-2: 24012
SwissProt-2: O54829
Organism-3: Rat
Gene ID-3: 54296
SwissProt-3: P49803
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm, cytosol . Cytoplasm . Cell membrane . Membrane ; Peripheral membrane protein ; Cytoplasmic side . Interaction with PKD1 promotes location at the cell membrane (PubMed:10339594). Interaction with RGS7BP promotes location at the cell membrane (PubMed:15897264). .