U-Blot® Rho A Polyclonal Antibody

Name: U-Blot® Rho A Polyclonal Antibody
SKU: WP14278
Availability: InStock

$268.00

Size:50μL

SKU: WP14278-50

Catalog No.: WP14278

Specification: 50μL/100μL

Stock: In stock

U-Blot® Rho A Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified. [provided by RefSeq, Sep 2015],

Product Overview

Catalog No.: WP14278
SKU: WP14278-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Rho A
Reactivity: Human,Mouse,Rat
Application: IF,WB,IHC,ELISA
MW(Calculated): --
MW(Observed): 22kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: IF 1:50-200;WB 1:500-1:2000;IHC 1:100-1:300;ELISA 1:5000;Not yet tested in other applications;
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human RhoA. AA range:144-193
Sequence: --
Specificity: Rho A Polyclonal Antibody detects endogenous levels of Rho A protein.
Gene Name: RHOA
Protein Name: Transforming protein RhoA
Other Name: RHOA;ARH12;ARHA;RHO12;Transforming protein RhoA;Rho cDNA clone 12;h12
Organism-1: Human
Gene ID-1: 387
SwissProt-1: P61586
Organism-2: Mouse
Gene ID-2: 11848
SwissProt-2: Q9QUI0
Organism-3: Rat
Gene ID-3: 117273
SwissProt-3: P61589
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytoskeleton. Cleavage furrow. Cytoplasm, cell cortex . Midbody. Cell projection, lamellipodium . Cell projection, dendrite . Nucleus . Localized to cell-cell contacts in calcium-treated keratinocytes (By similarity). Translocates to the equatorial region before furrow formation in a ECT2-dependent manner. Localizes to the equatorial cell cortex (at the site of the presumptive furrow) in early anaphase in an activated form and in a myosin- and actin-independent manner. .