U-Blot® Septin 2 Polyclonal Antibody

Name: U-Blot® Septin 2 Polyclonal Antibody
SKU: WP14436
Availability: InStock

$268.00

Size:50μL

SKU: WP14436-50

Catalog No.: WP14436

Specification: 50μL/100μL

Stock: In stock

U-Blot® Septin 2 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：function:Required for normal progress through mitosis. Involved in cytokinesis.,similarity:Belongs to the septin family.,subcellular location:Accumulates near the contractile ring from anaphase through telophase, and finally condenses into the midbody. In interphase and postmitotic cells, localised to fibrous or granular structures, depending on the growth state of the cell.,subunit:Monomer, and homodimer. Nucleotide binding promotes dimerization. Heterohexamer composed of two heterotrimers containing one copy each of SEPT2, SEPT6 and SEPT7. The asymmetrical heterotrimers associate head-to-head to form a hexameric unit that assembles into filaments.,

Product Overview

Catalog No.: WP14436
SKU: WP14436-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Septin 2
Reactivity: Human,Mouse,Rat
Application: WB,IHC
MW(Calculated): --
MW(Observed): 41kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000;IHC 1:50-300
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human SEPT2. AA range:103-152
Sequence: --
Specificity: Septin 2 Polyclonal Antibody detects endogenous levels of Septin 2 protein.
Gene Name: SEPT2
Protein Name: Septin-2
Other Name: SEPT2;DIFF6;KIAA0158;NEDD5;Septin-2;Neural precursor cell expressed developmentally down-regulated protein 5;NEDD-5
Organism-1: Human
Gene ID-1: 4735
SwissProt-1: Q15019
Organism-2: Mouse
Gene ID-2: 18000
SwissProt-2: P42208
Organism-3: Rat
Gene ID-3: 117515
SwissProt-3: Q91Y81
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm . Cytoplasm, cytoskeleton . Cytoplasm, cytoskeleton, spindle . Chromosome, centromere, kinetochore . Cleavage furrow . Midbody . Cytoplasm, cell cortex . Cell projection, cilium membrane . Cell projection, cilium, flagellum . In metaphase cells, localized within the microtubule spindle. At the metaphase plate, in close apposition to the kinetochores of the congressed chromosomes. In cells undergoing cytokinesis, localized to the midbody, the ingressing cleavage furrow, and the central spindle. During bacterial infection, displays a collar shape structure next to actin at the pole of invading bacteria. In epithelial cells, colocalizes with polyglutamylated tubulin around the trans-Golgi network, as well as juxatnuclear and proximal Golgi apparatus. Localizes at the base of the cilia near the morphological distinction between the cilia and plasma membranes. Found in the sperm annulus (PubMed:25588830). .