U-Blot® Siah-1/2 Polyclonal Antibody

Name: U-Blot® Siah-1/2 Polyclonal Antibody
SKU: WP14481
Availability: InStock

$268.00

Size:50μL

SKU: WP14481-50

Catalog No.: WP14481

Specification: 50μL/100μL

Stock: In stock

U-Blot® Siah-1/2 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP14481
SKU: WP14481-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Siah-1/2
Reactivity: Human,Mouse,Rat
Application: WB,IHC,IF,ELISA
MW(Calculated): --
MW(Observed): 34kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:10000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human SIAH1. AA range:181-230
Sequence: --
Specificity: Siah-1/2 Polyclonal Antibody detects endogenous levels of Siah-1/2 protein.
Gene Name: SIAH1/SIAH2
Protein Name: E3 ubiquitin-protein ligase SIAH1/2
Other Name: SIAH1;HUMSIAH;E3 ubiquitin-protein ligase SIAH1;Seven in absentia homolog 1;Siah-1;Siah-1a;SIAH2;E3 ubiquitin-protein ligase SIAH2;Seven in absentia homolog 2;Siah-2;hSiah2
Organism-1: Human
Gene ID-1: 6477;6478
SwissProt-1: Q8IUQ4;O43255
Organism-2: Mouse
Gene ID-2: 20439
SwissProt-2: --
Organism-3: Rat
Gene ID-3: 140941;140593
SwissProt-3: Q920M9;Q8R4T2
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm. Nucleus. Predominantly cytoplasmic. Partially nuclear.