U-Blot® SNX1 Polyclonal Antibody

Name: U-Blot® SNX1 Polyclonal Antibody
SKU: WP14533
Availability: InStock

$268.00

Size:50μL

SKU: WP14533-50

Catalog No.: WP14533

Specification: 50μL/100μL

Stock: In stock

U-Blot® SNX1 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP14533
SKU: WP14533-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: SNX1
Reactivity: Human,Mouse,Rat
Application: WB,ELISA,IHC
MW(Calculated): --
MW(Observed): 60kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from the Internal region of human SNX1.
Sequence: --
Specificity: SNX1 Polyclonal Antibody detects endogenous levels of SNX1 protein.
Gene Name: SNX1
Protein Name: Sorting nexin-1
Other Name: SNX1;Sorting nexin-1
Organism-1: Human
Gene ID-1: 6642
SwissProt-1: Q13596
Organism-2: Mouse
Gene ID-2: 56440
SwissProt-2: Q9WV80
Organism-3: Rat
Gene ID-3: 84471
SwissProt-3: Q99N27
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Endosome membrane ; Peripheral membrane protein; Cytoplasmic side. Golgi apparatus, trans-Golgi network membrane ; Peripheral membrane protein ; Cytoplasmic side . Early endosome membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, lamellipodium . Enriched on tubular elements of the early endosome membrane. Binds preferentially to highly curved membranes enriched in phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) (PubMed:15498486). Colocalized with SORT1 to tubular endosomal membrane structures called endosome-to-TGN transport carriers (ETCs) which are budding from early endosome vacuoles just before maturing into late endosome vacuoles (PubMed:18088323). Colocalizes with DNAJC13 and Shiginella dysenteria toxin stxB on early endosomes (PubMed:19874558). Colocalized with F-actin at the leading edge of lamellipodia in a KALRN-dependent manner (PubMed:20604901). .