U-Blot® Topo I Polyclonal Antibody

Name: U-Blot® Topo I Polyclonal Antibody
SKU: WP14820
Availability: InStock

$268.00

Size:50μL

SKU: WP14820-50

Catalog No.: WP14820

Specification: 50μL/100μL

Stock: In stock

U-Blot® Topo I Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP14820
SKU: WP14820-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Topo I
Reactivity: Human,Mouse,Rat
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 90kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from the Internal region of human Topo I.
Sequence: --
Specificity: Topo I Polyclonal Antibody detects endogenous levels of Topo I protein.
Gene Name: TOP1
Protein Name: DNA topoisomerase 1
Other Name: TOP1;DNA topoisomerase 1;DNA topoisomerase I
Organism-1: Human
Gene ID-1: 7150
SwissProt-1: P11387
Organism-2: Mouse
Gene ID-2: 21969
SwissProt-2: Q04750
Organism-3: Rat
Gene ID-3: 64550
SwissProt-3: Q9WUL0
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus, nucleolus . Nucleus, nucleoplasm . Diffuse nuclear localization with some enrichment in nucleoli. On CPT treatment, cleared from nucleoli into nucleoplasm. Sumoylated forms found in both nucleoplasm and nucleoli.