U-Blot® Tsg 101 Polyclonal Antibody

Name: U-Blot® Tsg 101 Polyclonal Antibody
SKU: WP14879
Availability: InStock

$268.00

Size:50μL

SKU: WP14879-50

Catalog No.: WP14879

Specification: 50μL/100μL

Stock: In stock

U-Blot® Tsg 101 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP14879
SKU: WP14879-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Tsg 101
Reactivity: Human,Mouse,Rat,Monkey
Application: WB,IHC,IF,ELISA
MW(Calculated): --
MW(Observed): 45kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:5000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human TSG101. AA range:281-330
Sequence: --
Specificity: Tsg 101 Polyclonal Antibody detects endogenous levels of Tsg 101 protein.
Gene Name: TSG101
Protein Name: Tumor susceptibility gene 101 protein
Other Name: TSG101;Tumor susceptibility gene 101 protein;ESCRT-I complex subunit TSG101
Organism-1: Human
Gene ID-1: 7251
SwissProt-1: Q99816
Organism-2: Mouse
Gene ID-2: 22088
SwissProt-2: Q61187
Organism-3: Rat
Gene ID-3: 292925
SwissProt-3: Q6IRE4
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm . Early endosome membrane ; Peripheral membrane protein ; Cytoplasmic side . Late endosome membrane ; Peripheral membrane protein. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Midbody, Midbody ring . Nucleus . Mainly cytoplasmic. Membrane-associated when active and soluble when inactive. Nuclear localization is cell cycle-dependent. Interaction with CEP55 is required for localization to the midbody during cytokinesis. .