U-Blot® TWIK-1 Polyclonal Antibody

Name: U-Blot® TWIK-1 Polyclonal Antibody
SKU: WP14905
Availability: InStock

$268.00

Size:50μL

SKU: WP14905-50

Catalog No.: WP14905

Specification: 50μL/100μL

Stock: In stock

U-Blot® TWIK-1 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The product of this gene has not been shown to be a functional channel, however, it may require other non-pore-forming proteins for activity. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP14905
SKU: WP14905-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: TWIK-1
Reactivity: Human,Rat
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 38kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;ELISA 1:40000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human KCNK1. AA range:287-336
Sequence: --
Specificity: TWIK-1 Polyclonal Antibody detects endogenous levels of TWIK-1 protein.
Gene Name: KCNK1
Protein Name: Potassium channel subfamily K member 1
Other Name: KCNK1;HOHO1;KCNO1;TWIK1;Potassium channel subfamily K member 1;Inward rectifying potassium channel protein TWIK-1;Potassium channel KCNO1
Organism-1: Human
Gene ID-1: 3775
SwissProt-1: O00180
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: O08581
Organism-3: Rat
Gene ID-3: 59324
SwissProt-3: Q9Z2T2
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cell membrane ; Multi-pass membrane protein . Recycling endosome . Cell junction, synapse, synaptic cell membrane . Cytoplasmic vesicle . Perikaryon . Cell projection, dendrite . Cell projection . Apical cell membrane ; Multi-pass membrane protein . The heterodimer with KCNK2 is detected at the astrocyte cell membrane. Not detected at the astrocyte cell membrane when KCNK2 is absent. Detected on neuronal cell bodies, and to a lesser degree on neuronal cell projections. Detected on hippocampus dentate gyrus granule cell bodies and to a lesser degree on proximal dendrites. Detected at the apical cell membrane in stria vascularis in the cochlea. Detected at the apical cell membrane of vestibular dark cells situated between the crista and the utricle in the inner ear. Detected at the apical cell membrane in kidney proximal tubule segment S1 and in subapical compartments in segments S1, S2 and S3. Predominantly in cytoplasmic structures in kidney distal convoluted tubules and collecting ducts (By similarity). Detected at the apical cell membrane of bronchial epithelial cells (PubMed:21964404). .