U-Blot® ZNRF2 Polyclonal Antibody

Name: U-Blot® ZNRF2 Polyclonal Antibody
SKU: WP15092
Availability: InStock

$268.00

Size:50μL

SKU: WP15092-50

Catalog No.: WP15092

Specification: 50μL/100μL

Stock: In stock

U-Blot® ZNRF2 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：domain:The RING-type zinc finger domain is required for E3 ligase activity.,function:May play a role in the establisment and maintenance of neuronal transmission and plasticity via its ubiquitin ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.,pathway:Protein modification; protein ubiquitination.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 RING-type zinc finger.,subcellular location:Present in presynaptic plasma membranes in neurons.,subunit:Interacts with UBE2N.,tissue specificity:Highly expressed in the brain, with higher expression during development than in adult. Expressed also in mammary glands, testis, colon and kidney.,

Product Overview

Catalog No.: WP15092
SKU: WP15092-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: ZNRF2
Reactivity: Human,Mouse
Application: IHC,IF,ELISA
MW(Calculated): 24kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: IHC 1:100-1:300;IF 1:200-1:1000;ELISA 1:20000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from human ZNRF2. AA range:161-210
Sequence: --
Specificity: ZNRF2 Polyclonal Antibody detects endogenous levels of ZNRF2 protein.
Gene Name: ZNRF2
Protein Name: E3 ubiquitin-protein ligase ZNRF2
Other Name: ZNRF2;RNF202;E3 ubiquitin-protein ligase ZNRF2;Protein Ells2;RING finger protein 202;Zinc/RING finger protein 2
Organism-1: Human
Gene ID-1: 223082
SwissProt-1: Q8NHG8
Organism-2: Mouse
Gene ID-2: 387524
SwissProt-2: Q71FD5
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Endosome membrane ; Peripheral membrane protein . Lysosome membrane ; Peripheral membrane protein . Cell junction, synapse, presynaptic cell membrane ; Peripheral membrane protein .