U-Blot® Fascin 1 Polyclonal Antibody

Name: U-Blot® Fascin 1 Polyclonal Antibody
SKU: WP15286
Availability: InStock

$268.00

Size:50μL

SKU: WP15286-50

Catalog No.: WP15286

Specification: 50μL/100μL

Stock: In stock

U-Blot® Fascin 1 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011],

Product Overview

Catalog No.: WP15286
SKU: WP15286-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Fascin
Reactivity: Human,Mouse,Rat
Application: WB,IHC,IF,ELISA
MW(Calculated): --
MW(Observed): 55kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human FSCN1. AA range:261-310
Sequence: --
Specificity: Fascin 1 Polyclonal Antibody detects endogenous levels of Fascin 1 protein.
Gene Name: FSCN1
Protein Name: Fascin (55 kDa actin-bundling protein) (Singed-like protein) (p55)
Other Name: FSCN1;FAN1;HSN;SNL;Fascin;55 kDa actin-bundling protein;Singed-like protein;p55
Organism-1: Human
Gene ID-1: 6624
SwissProt-1: Q16658
Organism-2: Mouse
Gene ID-2: 14086
SwissProt-2: Q61553
Organism-3: Rat
Gene ID-3: 683788
SwissProt-3: P85845
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm, cytosol . Cytoplasm, cell cortex . Cytoplasm, cytoskeleton . Cytoplasm, cytoskeleton, stress fiber . Cell projection, filopodium . Cell projection, invadopodium . Cell projection, microvillus . Cell junction . Colocalized with RUFY3 and F-actin at filipodia of the axonal growth cone. Colocalized with DBN1 and F-actin at the transitional domain of the axonal growth cone (By similarity). .