U-Blot® HPA1 Polyclonal Antibody

Name: U-Blot® HPA1 Polyclonal Antibody
SKU: WP15400
Availability: InStock

$268.00

Size:50μL

SKU: WP15400-50

Catalog No.: WP15400

Specification: 50μL/100μL

Stock: In stock

U-Blot® HPA1 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：Heparan sulfate proteoglycans are major components of the basement membrane and extracellular matrix. The protein encoded by this gene is an enzyme that cleaves heparan sulfate proteoglycans to permit cell movement through remodeling of the extracellular matrix. In addition, this cleavage can release bioactive molecules from the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011],

Product Overview

Catalog No.: WP15400
SKU: WP15400-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: HPA1
Reactivity: Human,Rat,Mouse,
Application: WB,IHC,IF,ELISA
MW(Calculated): --
MW(Observed): 62kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:20000;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human HPSE. AA range:241-290
Sequence: --
Specificity: HPA1 Polyclonal Antibody detects endogenous levels of HPA1 protein.
Gene Name: HPSE
Protein Name: Heparanase
Other Name: HPSE;HEP;HPA;HPA1;HPR1;HPSE1;HSE1;Heparanase;Endo-glucoronidase;Heparanase-1;Hpa1
Organism-1: Human
Gene ID-1: 10855
SwissProt-1: Q9Y251
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q6YGZ1
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Lysosome membrane; Peripheral membrane protein. Secreted. Nucleus. Proheparanase is secreted via vesicles of the Golgi. Interacts with cell membrane heparan sulfate proteoglycans (HSPGs). Endocytosed and accumulates in endosomes. Transferred to lysosomes where it is proteolytically cleaved to produce the active enzyme. Under certain stimuli, transferred to the cell surface. Associates with lipid rafts. Colocalizes with SDC1 in endosomal/lysosomal vesicles. Accumulates in perinuclear lysosomal vesicles. Heparin retains proheparanase in the extracellular medium (By similarity). .