U-Blot® Bag-1 Polyclonal Antibody

Name: U-Blot® Bag-1 Polyclonal Antibody
SKU: WP15406
Availability: InStock

$268.00

Size:50μL

SKU: WP15406-50

Catalog No.: WP15406

Specification: 50μL/100μL

Stock: In stock

U-Blot® Bag-1 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X. [provided by RefSeq, Feb 2010],

Product Overview

Catalog No.: WP15406
SKU: WP15406-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Bag-1
Reactivity: Human,Rat,Mouse,
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 35kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human BAG1. AA range:41-90
Sequence: --
Specificity: Bag-1 Polyclonal Antibody detects endogenous levels of Bag-1 protein.
Gene Name: BAG1
Protein Name: BAG family molecular chaperone regulator 1
Other Name: Bag 1;BAG family molecular chaperone regulator 1;BAG-1;BAG1;BAG1_HUMAN;BCL 2 Associated Athanogene 1;BCL 2 associated athanogene;BCL 2 binding athanogene 1;Bcl-2-associated athanogene 1;BCL2 associated athanogene 1;BCL2 associated athanogene;Glucocorticoid receptor-associated protein RAP46;HAP1;Haptoglobin;RAP 46;RAP46.
Organism-1: Human
Gene ID-1: 573
SwissProt-1: Q99933
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q60739
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: [Isoform 1]: Nucleus. Cytoplasm. Isoform 1 localizes predominantly to the nucleus.; [Isoform 2]: Cytoplasm. Nucleus. Isoform 2 localizes to the cytoplasm and shuttles into the nucleus in response to heat shock.; [Isoform 4]: Cytoplasm. Nucleus. Isoform 4 localizes predominantly to the cytoplasm. The cellular background in which it is expressed can influence whether it resides primarily in the cytoplasm or is also found in the nucleus. In the presence of BCL2, localizes to intracellular membranes (what appears to be the nuclear envelope and perinuclear membranes) as well as punctate cytosolic structures suggestive of mitochondria.