U-Blot® Apaf-1 Polyclonal Antibody

Name: U-Blot® Apaf-1 Polyclonal Antibody
SKU: WP15423
Availability: InStock

$268.00

Size:50μL

SKU: WP15423-50

Catalog No.: WP15423

Specification: 50μL/100μL

Stock: In stock

U-Blot® Apaf-1 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP15423
SKU: WP15423-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: APAF1
Reactivity: Human,Mouse,Rat
Application: WB,IHC,IF,ELISA
MW(Calculated): --
MW(Observed): 135kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:20000;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human APAF1. AA range:501-550
Sequence: --
Specificity: Apaf-1 Polyclonal Antibody detects endogenous levels of Apaf-1 protein.
Gene Name: APAF1
Protein Name: Apoptotic protease-activating factor 1
Other Name: APAF1;KIAA0413;Apoptotic protease-activating factor 1;APAF-1
Organism-1: Human
Gene ID-1: 317
SwissProt-1: O14727
Organism-2: Mouse
Gene ID-2: 11783
SwissProt-2: O88879
Organism-3: Rat
Gene ID-3: 78963
SwissProt-3: Q9EPV5
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm .