U-Blot® gp91-phox Polyclonal Antibody

Name: U-Blot® gp91-phox Polyclonal Antibody
SKU: WP15428
Availability: InStock

$268.00

Size:50μL

SKU: WP15428-50

Catalog No.: WP15428

Specification: 50μL/100μL

Stock: In stock

U-Blot® gp91-phox Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP15428
SKU: WP15428-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: gp91-phox
Reactivity: Human,Mouse
Application: WB,IHC,IF,ELISA
MW(Calculated): --
MW(Observed): 70kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:20000;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human CYBB. AA range:111-160
Sequence: --
Specificity: gp91-phox Polyclonal Antibody detects endogenous levels of gp91-phox protein.
Gene Name: CYBB
Protein Name: Cytochrome b-245 heavy chain
Other Name: CYBB;NOX2;Cytochrome b-245 heavy chain;CGD91-phox;Cytochrome b;558;subunit beta;Cytochrome b558 subunit beta;Heme-binding membrane glycoprotein gp91phox;NADPH oxidase 2Neutrophil cytochrome b 91 kDa polypeptide;Superoxide-generating NADPH oxidase heavy chain subunit;gp91-1;gp91-phox;p22 phagocyte B-cytochrome
Organism-1: Human
Gene ID-1: 1536
SwissProt-1: P04839
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q61093
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cell membrane; Multi-pass membrane protein. As unassembled monomer may localize to the endoplasmic reticulum. .