U-Blot® EF-1 α1/2 Polyclonal Antibody

Name: U-Blot® EF-1 α1/2 Polyclonal Antibody
SKU: WP15520
Availability: InStock

$268.00

Size:50μL

SKU: WP15520-50

Catalog No.: WP15520

Specification: 50μL/100μL

Stock: In stock

U-Blot® EF-1 α1/2 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expressed in brain, heart and skeletal muscle. This isoform is identified as an autoantigen in 66% of patients with Felty syndrome. This gene has been found to have multiple copies on many chromosomes, some of which, if not all, represent different pseudogenes. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP15520
SKU: WP15520-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: EF-1 α1/2
Reactivity: Human,Mouse,Rat
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 50kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;ELISA 1:20000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from the N-terminal region of human EF-1 α1/2.
Sequence: --
Specificity: EF-1 α1/2 Polyclonal Antibody detects endogenous levels of EF-1 α1/2 protein.
Gene Name: EEF1A1/EEF1A2/EEF1A1P5
Protein Name: Elongation factor 1-alpha 1/Elongation factor 1-alpha 2/Putative elongation factor 1-alpha-like 3
Other Name: EEF1A1;EEF1A;EF1A;LENG7;Elongation factor 1-alpha 1;EF-1-alpha-1;Elongation factor Tu;EF-Tu;Eukaryotic elongation factor 1 A-1;eEF1A-1;Leukocyte receptor cluster member 7;EEF1A2;EEF1AL;STN;Elongation factor 1-alpha 2;EF-1-alpha-2;Eukaryotic elongation factor 1 A-2;eEF1A-2;Statin-S1;EEF1A1P5;EEF1AL3;Putative elongation factor 1-alpha-like 3;EF-1-alpha-like 3;Eukaryotic elongation factor 1 A-like 3;eEF1A-like 3;Eukaryotic translation elongation factor 1 alpha-1 pseudogene 5
Organism-1: Human
Gene ID-1: 1915;1917
SwissProt-1: P68104;Q05639;Q5VTE0
Organism-2: Mouse
Gene ID-2: 13627;13628
SwissProt-2: --
Organism-3: Rat
Gene ID-3: 171361;24799
SwissProt-3: P62630;P62632
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm . Nucleus . Nucleus, nucleolus . Cell membrane . Colocalizes with DLC1 at actin-rich regions in the cell periphery (PubMed:19158340). Translocates together with ZPR1 from the cytoplasm to the nucleus and nucleolus after treatment with mitogens (PubMed:8650580). Localization at the cell membrane depends on EEF1A1 phosphorylation status and the presence of PPP1R16B (PubMed:26497934). .