U-Blot® Glut4 Polyclonal Antibody

U-Blot® Glut4 Polyclonal Antibody
U-Blot® Glut4 Polyclonal Antibody
$268.00
Size:50μL
SKU: WP15537-50

Catalog No.: WP15537

Specification: 50μL/100μL

Stock: In stock

U-Blot® Glut4 Polyclonal Antibody Learn more

Product information

Background:This gene is a member of the solute carrier family 2 (facilitated glucose transporter) family and encodes a protein that functions as an insulin-regulated facilitative glucose transporter. In the absence of insulin, this integral membrane protein is sequestered within the cells of muscle and adipose tissue. Within minutes of insulin stimulation, the protein moves to the cell surface and begins to transport glucose across the cell membrane. Mutations in this gene have been associated with noninsulin-dependent diabetes mellitus (NIDDM). [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.
WP15537
SKU
WP15537-50
Category
Polyclonal antibodies
Product Type
Other
Size
50μL/100μL
Stock Status
In stock
Available Stock
20
Minimum Order Quantity
1

Storage & Compliance

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only
Yes

Additional Specifications

Target
Glut4
Reactivity
Human,Mouse,Rat
Application
WB,IHC,IF,ELISA
MW(Calculated)
--
MW(Observed)
56kD
Host Species
Rabbit
Isotype
IgG
Conjugate/Modification
Unmodified
Modification site
--
Recommended Dilution Ratio
WB 1:500-1:2000;IHC: 1:100-300;ELISA 1:20000;IF 1:100-300;Not yet tested in other applications.
Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
--
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
--
storageCondition
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone No.
--
Immunogen
The antiserum was produced against synthesized peptide derived from the N-terminal region of human SLC2A4. AA range:21-70
Sequence
--
Specificity
Glut4 Polyclonal Antibody detects endogenous levels of Glut4 protein.
Gene Name
SLC2A4
Protein Name
Solute carrier family 2 facilitated glucose transporter member 4
Other Name
SLC2A4;GLUT4;Solute carrier family 2, facilitated glucose transporter member 4;Glucose transporter type 4, insulin-responsive;GLUT-4
Organism-1
Human
Gene ID-1
6517
SwissProt-1
P14672
Organism-2
Mouse
Gene ID-2
20528
SwissProt-2
P14142
Organism-3
Rat
Gene ID-3
25139
SwissProt-3
P19357
Organism-4
--
gene ID-4
--
SwissProt-4
--
Cellular Localization
Cell membrane ; Multi-pass membrane protein . Endomembrane system ; Multi-pass membrane protein . Cytoplasm, perinuclear region . Localizes primarily to the perinuclear region, undergoing continued recycling to the plasma membrane where it is rapidly reinternalized (PubMed:8300557). The dileucine internalization motif is critical for intracellular sequestration (PubMed:8300557). Insulin stimulation induces translocation to the cell membrane (By similarity). .

Tech Support

ucallm

01

Documents

Datasheet, COA, SDS, and protocol files can be requested from technical support.

02

Storage & Handling

Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
06

Contact Support

Emailinfo@ucallmlabs.com

Phone+(1)-866-986-9598

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Keywords:Polyclonal antibodies