- Target
- BST-2
- Reactivity
- Human,Rat,Mouse,
- Application
- WB,IHC,IF,ELISA
- MW(Calculated)
- --
- MW(Observed)
- 20kD
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:10000;IF 1:50-200
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- 1 mg/ml
- Clonality
- Polyclonal
- Clone No.
- --
- Immunogen
- The antiserum was produced against synthesized peptide derived from the Internal region of human BST2. AA range:101-150
- Sequence
- --
- Specificity
- BST-2 Polyclonal Antibody detects endogenous levels of BST-2 protein.
- Gene Name
- BST2
- Protein Name
- Bone marrow stromal antigen 2
- Other Name
- BST2;Bone marrow stromal antigen 2;BST-2;HM1.24 antigen;Tetherin;CD317
- Organism-1
- Human
- Gene ID-1
- 684
- SwissProt-1
- Q10589
- Organism-2
- Mouse
- Gene ID-2
- --
- SwissProt-2
- Q8R2Q8
- Organism-3
- --
- Gene ID-3
- --
- SwissProt-3
- --
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Golgi apparatus, trans-Golgi network. Cell membrane ; Single-pass type II membrane protein. Cell membrane ; Lipid-anchor, GPI-anchor . Membrane raft. Cytoplasm. Apical cell membrane . Shuttles between the cell membrane, where it is present predominantly in membrane/lipid rafts, and the trans-Golgi network. Forms a complex with MMP14 and localizes to the cytoplasm.; Golgi apparatus, trans-Golgi network . Late endosome . (Microbial infection) HIV-1 VPU and HIV-2 ENV can target it to the trans-Golgi network thus sequestering it away from virus assembly sites on the cell membrane. Targeted to late endosomes upon KSHV infection and subsequent ubiquitination. .