U-Blot® SIRP-α1/β1 Polyclonal Antibody

Name: U-Blot® SIRP-α1/β1 Polyclonal Antibody
SKU: WP15620
Availability: InStock

$268.00

Size:50μL

SKU: WP15620-50

Catalog No.: WP15620

Specification: 50μL/100μL

Stock: In stock

U-Blot® SIRP-α1/β1 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein can be phosphorylated by tyrosine kinases. The phospho-tyrosine residues of this PTP have been shown to recruit SH2 domain containing tyrosine phosphatases (PTP), and serve as substrates of PTPs. This protein was found to participate in signal transduction mediated by various growth factor receptors. CD47 has been demonstrated to be a ligand for this receptor protein. This gene and its product share very high similarity with several other members of the SIRP family. These related genes are located in close proximity to each other on chromosome 20p13. Multiple alternati

Product Overview

Catalog No.: WP15620
SKU: WP15620-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: SIRP-α1/β1
Reactivity: Human,Rat,Mouse,
Application: WB,IHC,IF,ELISA
MW(Calculated): --
MW(Observed): 55kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;IHC: 1:100-1:300;ELISA 1:10000;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human SIRPA/SIRPB1. AA range:281-330
Sequence: --
Specificity: SIRP-α1/β1 Polyclonal Antibody detects endogenous levels of SIRP-α1/β1 protein.
Gene Name: SIRPA/SIRPB1
Protein Name: Tyrosine-protein phosphatase non-receptor type substrate 1/Signal-regulatory protein beta-1 isoform 3
Other Name: SIRPA;BIT;MFR;MYD1;PTPNS1;SHPS1;SIRP;Tyrosine-protein phosphatase non-receptor type substrate 1;SHP substrate 1;SHPS-1;Brain Ig-like molecule with tyrosine-based activation motifs;Bit;CD172 antigen-like family member A;Inhibitory receptor SHPS-1;Macrophage fusion receptor;MyD-1 antigen;Signal-regulatory protein alpha-1;Sirp-alpha-1;Signal-regulatory protein alpha-2;Sirp-alpha-2;Signal-regulatory protein alpha-3;Sirp-alpha-3;p84;CD172a;SIRPB1;Signal-regulatory protein beta-1 isoform 3;SIRP-beta-1 isoform 3
Organism-1: Human
Gene ID-1: 140885;10326;100653194
SwissProt-1: P78324;Q5TFQ8
Organism-2: Mouse
Gene ID-2: 19261
SwissProt-2: --
Organism-3: Rat
Gene ID-3: 25528
SwissProt-3: P97710
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Membrane; Single-pass type I membrane protein.