U-Blot® EMAP II Polyclonal Antibody

Name: U-Blot® EMAP II Polyclonal Antibody
SKU: WP15637
Availability: InStock

$268.00

Size:50μL

SKU: WP15637-50

Catalog No.: WP15637

Specification: 50μL/100μL

Stock: In stock

U-Blot® EMAP II Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：The protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20. [provided by RefSeq, Dec 2008],

Product Overview

Catalog No.: WP15637
SKU: WP15637-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: EMAP II
Reactivity: Human,Mouse
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 34kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-1:2000;ELISA 1:10000;Not yet tested in other applications.
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human AIMP1. AA range:91-140
Sequence: --
Specificity: EMAP II Polyclonal Antibody detects endogenous levels of EMAP II protein.
Gene Name: AIMP1
Protein Name: Aminoacyl tRNA synthase complex-interacting multifunctional protein 1
Other Name: AIMP1;EMAP2;SCYE1;Aminoacyl tRNA synthase complex-interacting multifunctional protein 1;Multisynthase complex auxiliary component p43
Organism-1: Human
Gene ID-1: 9255
SwissProt-1: Q12904
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: P31230
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus . Cytoplasm, cytosol . Secreted . Endoplasmic reticulum . Golgi apparatus . Enriched in secretory vesicles of pancreatic alpha cells and secreted from the pancreas in response to low glucose levels (By similarity). Secreted in response to hypoxia (PubMed:10850427). Also secreted in response to both apoptotic and necrotic cell death. .