U-Blot® RPGF6 Polyclonal Antibody

Name: U-Blot® RPGF6 Polyclonal Antibody
SKU: WP1570
Availability: InStock

$268.00

Size:50μL

SKU: WP1570-50

Catalog No.: WP1570

Specification: 50μL/100μL

Stock: In stock

U-Blot® RPGF6 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：function:Guanine nucleotide exchange factor (GEF) for Rap1A, Rap2A and M-Ras GTPases. Does not interact with cAMP.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 cyclic nucleotide-binding domain.,similarity:Contains 1 N-terminal Ras-GEF domain.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 1 Ras-associating domain.,similarity:Contains 1 Ras-GEF domain.,subcellular location:Upon binding to M-Ras, it translocates to the plasma membrane.,subunit:Interacts with the second PDZ domain of human PTP1e.,tissue specificity:Isoform 3 has highest expression levels in the brain, heart, liver, lung and placenta and is barely detectable in skeletal muscle, kidney and pancreas.,

Product Overview

Catalog No.: WP1570
SKU: WP1570-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: RPGF6
Reactivity: Human
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 176kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000;ELISA 1:5000-20000
Form: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human protein . at AA range: 460-540
Sequence: --
Specificity: RPGF6 Polyclonal Antibody detects endogenous levels of protein.
Gene Name: RAPGEF6 PDZGEF2
Protein Name: Rap guanine nucleotide exchange factor 6 (PDZ domain-containing guanine nucleotide exchange factor 2) (PDZ-GEF2) (RA-GEF-2)
Other Name: --
Organism-1: Human
Gene ID-1: 51735
SwissProt-1: Q8TEU7
Organism-2: --
Gene ID-2: --
SwissProt-2: --
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm . Cell membrane . Upon binding to M-Ras, it translocates to the plasma membrane.