- Target
- Atg9a
- Reactivity
- Human,Mouse,Rat
- Application
- WB,ELISA
- MW(Calculated)
- --
- MW(Observed)
- 85kD
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:500-2000;ELISA 1:10000-20000
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- 1 mg/ml
- Clonality
- Polyclonal
- Clone No.
- --
- Immunogen
- Synthetic Peptide of Atg9a
- Sequence
- --
- Specificity
- Atg9a Polyclonal Antibody detects endogenous levels of Atg9a
- Gene Name
- ATG9A APG9L1
- Protein Name
- Atg9a
- Other Name
- ATG9 autophagy related 9 homolog A;S. cerevisiae;
- Organism-1
- Human
- Gene ID-1
- 79065
- SwissProt-1
- Q7Z3C6
- Organism-2
- Mouse
- Gene ID-2
- --
- SwissProt-2
- Q68FE2
- Organism-3
- Rat
- Gene ID-3
- --
- SwissProt-3
- Q5FWU3
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Preautophagosomal structure membrane ; Multi-pass membrane protein . Cytoplasmic vesicle, autophagosome membrane ; Multi-pass membrane protein . Golgi apparatus, trans-Golgi network membrane ; Multi-pass membrane protein . Late endosome membrane ; Multi-pass membrane protein . Recycling endosome membrane ; Multi-pass membrane protein . Endoplasmic reticulum membrane ; Multi-pass membrane protein . Mitochondrion membrane ; Multi-pass membrane protein . Mainly localizes to the trans-Golgi network (TGN) and the endosomal system; cycles between them though vesicle trafficking (PubMed:27316455, PubMed:27663665). Export from the TGN to promote formation of autophagosomes is mediated by the AP-4 complex (PubMed:29180427, PubMed:30262884). Under amino acid starvation or rapamycin treatment, redistributes to preautophagosomal structure/phagophore assembly site (PAS) (PubMed:16940348). The starvation-induced redistribution depends on ULK1, ATG13, as well as SH3GLB1 (PubMed:16940348). Upon autophagy induction, a small portion transiently localizes to the autophagic membranes (PubMed:22456507). Recruited to damaged mitochondria during mitophagy in a RIMOC1-dependent manner (PubMed:34432599). .