U-Blot® Bob 1 Polyclonal Antibody

Name: U-Blot® Bob 1 Polyclonal Antibody
SKU: WP15907
Availability: InStock

$268.00

Size:50μL

SKU: WP15907-50

Catalog No.: WP15907

Specification: 50μL/100μL

Stock: In stock

U-Blot® Bob 1 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：disease:A chromosomal aberration involving POU2AF1/OBF1 may be a cause of a form of B-cell leukemia. Translocation t(3;11)(q27;q23) with BCL6.,function:Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers.,PTM:Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation.,similarity:Belongs to the POU2AF1 family.,tissue specificity:B-cell specific.,

Product Overview

Catalog No.: WP15907
SKU: WP15907-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Bob 1
Reactivity: Human,Mouse
Application: IHC,IF,ELISA
MW(Calculated): --
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: IHC 1:50-200;ELISA 1:10000-20000;IF 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthetic peptide from human protein at AA range: 201-250
Sequence: --
Specificity: The antibody detects endogenous Bob 1
Gene Name: POU2AF1 OBF1
Protein Name: POU domain class 2-associating factor 1 (B-cell-specific coactivator OBF-1) (BOB-1) (OCA-B) (OCT-binding factor 1)
Other Name: POU domain class 2-associating factor 1;B-cell-specific coactivator OBF-1;BOB-1;OCA-B;OCT-binding factor 1;
Organism-1: Human
Gene ID-1: 5450
SwissProt-1: Q16633
Organism-2: Mouse
Gene ID-2: 18985
SwissProt-2: Q64693
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus .