U-Blot® RAB21 Polyclonal Antibody

Name: U-Blot® RAB21 Polyclonal Antibody
SKU: WP1591
Availability: InStock

$268.00

Size:50μL

SKU: WP1591-50

Catalog No.: WP1591

Specification: 50μL/100μL

Stock: In stock

U-Blot® RAB21 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene belongs to the Rab family of monomeric GTPases, which are involved in the control of cellular membrane traffic. The encoded protein plays a role in the targeted trafficking of integrins via its association with integrin alpha tails. As a consequence, the encoded protein is involved in the regulation of cell adhesion and migration. Expression of this gene is associated with a poor prognosis for glioma patients. This gene is downregulated by the tumor suppressor miR-200b, and miRNA-200b is itself downregulated in glioma tissues. [provided by RefSeq, Nov 2015],

Product Overview

Catalog No.: WP1591
SKU: WP1591-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: RAB21
Reactivity: Human,Rat,Mouse
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 24kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000;ELISA 1:5000-20000
Form: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human protein . at AA range: 60-140
Sequence: --
Specificity: RAB21 Polyclonal Antibody detects endogenous levels of protein.
Gene Name: RAB21 KIAA0118
Protein Name: Ras-related protein Rab-21
Other Name: --
Organism-1: Human
Gene ID-1: 23011
SwissProt-1: Q9UL25
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: P35282
Organism-3: Rat
Gene ID-3: --
SwissProt-3: Q6AXT5
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Endoplasmic reticulum membrane ; Lipid-anchor . Golgi apparatus, trans-Golgi network . Golgi apparatus membrane . Early endosome membrane . Cytoplasmic vesicle membrane . Cleavage furrow . Cell projection, neuron projection . Colocalizes with ANKRD27 and VAMP7 in neurites (By similarity). In nonpolarized epithelial Caco-2 cells, found in the endoplasmic reticulum; in polarized cells, observed in vesicles in the apical cytoplasm (PubMed:10887961). During mitosis, in mid-telophase, localized in the ingressing cleavage furrow (PubMed:18804435). In late telophase, detected at the opposite poles of the daughter cells, in vesicles at the base of lamellipodia formed by the separating daughter cells (PubMed:18804435). .