U-Blot® GLI-1 Polyclonal Antibody

Name: U-Blot® GLI-1 Polyclonal Antibody
SKU: WP15984
Availability: InStock

$268.00

Size:50μL

SKU: WP15984-50

Catalog No.: WP15984

Specification: 50μL/100μL

Stock: In stock

U-Blot® GLI-1 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes a member of the Kruppel family of zinc finger proteins. The encoded transcription factor is activated by the sonic hedgehog signal transduction cascade and regulates stem cell proliferation. The activity and nuclear localization of this protein is negatively regulated by p53 in an inhibitory loop. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009],

Product Overview

Catalog No.: WP15984
SKU: WP15984-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: GLI-1
Reactivity: Human,Mouse
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 120kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000;ELISA 1:10000-20000
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human GLI-1. at AA range: 460-490
Sequence: --
Specificity: This antibody detects endogenous levels of GLI-1
Gene Name: GLI1 GLI
Protein Name: GLI-1
Other Name: Zinc finger protein GLI1;Glioma-associated oncogene;Oncogene GLI;
Organism-1: Human
Gene ID-1: 2735
SwissProt-1: P08151
Organism-2: Mouse
Gene ID-2: 14632
SwissProt-2: P47806
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm . Nucleus . Tethered in the cytoplasm by binding to SUFU (PubMed:10806483). Activation and translocation to the nucleus is promoted by interaction with STK36 (PubMed:10806483). Phosphorylation by ULK3 may promote nuclear localization (PubMed:19878745). Translocation to the nucleus is promoted by interaction with ZIC1 (PubMed:11238441). .; [Isoform 2]: Cytoplasm . Nucleus .