U-Blot® LRWD1 rabbit pAb

Name: U-Blot® LRWD1 rabbit pAb
SKU: WP16248
Availability: InStock

$268.00

Size:50μL

SKU: WP16248-50

Catalog No.: WP16248

Specification: 50μL/100μL

Stock: In stock

U-Blot® LRWD1 rabbit pAb Learn more

Product details Specifications Q & A Education

Background：The protein encoded by this gene interacts with components of the origin recognition complex (ORC) and regulates the formation of the prereplicative complex. The encoded protein stabilizes the ORC and therefore aids in DNA replication. This protein is required for the G1/S phase transition of the cell cycle. In addition, the encoded protein binds to trimethylated histone H3 in heterochromatin and recruits the ORC and lysine methyltransferases, which help maintain the repressive heterochromatic state. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015],

Product Overview

Catalog No.: WP16248
SKU: WP16248-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: LRWD1
Reactivity: Human,Mouse
Application: WB,IHC
MW(Calculated): 71kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000;IHC 1:50-300
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human LRWD1 AA range: 395-445
Sequence: --
Specificity: This antibody detects endogenous levels of LRWD1 at Human/Mouse
Gene Name: LRWD1 ORCA
Protein Name: LRWD1
Other Name: --
Organism-1: Human
Gene ID-1: 222229
SwissProt-1: Q9UFC0
Organism-2: Mouse
Gene ID-2: 71735
SwissProt-2: Q8BUI3
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus . Chromosome, centromere. Chromosome, telomere. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Chromosome, centromere, kinetochore . Localizes to heterochromatin during G1 phase. Restricted to centromeres or telomeres as cells progress though S phase. When cells enter mitosis, relocalizes to centromeres. Recruitment to pericentric heterochromatin largely depends on the presence of H3K9me3.