- Target
- K1731
- Reactivity
- Human,Mouse,Rat
- Application
- IHC,IF
- MW(Calculated)
- 286kD
- MW(Observed)
- --
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- IHC 1:50-200;IF 1:50-200
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- 1 mg/ml
- Clonality
- Polyclonal
- Clone No.
- --
- Immunogen
- Synthesized peptide derived from human K1731 AA range: 208-258
- Sequence
- --
- Specificity
- This antibody detects endogenous levels of K1731 at Human/Mouse/Rat
- Gene Name
- KIAA1731
- Protein Name
- K1731
- Other Name
- --
- Organism-1
- Human
- Gene ID-1
- 85459
- SwissProt-1
- Q9C0D2
- Organism-2
- Mouse
- Gene ID-2
- 319675
- SwissProt-2
- Q8BQ48
- Organism-3
- Rat
- Gene ID-3
- --
- SwissProt-3
- A4L9P8
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, spindle . Cytoplasm, cytoskeleton . Associates with both of the converted centrioles during G1 but becomes more enriched at the newly formed daughter (or unconverted) centrioles during S, G2, and early M phases (PubMed:25131205, PubMed:32060285). In early S phase, localized at the procentriolar microtubule wall and enriched at the proximal ends of the centrioles in CENPJ- and CEP135-dependent manner (PubMed:27185865). Colocalizes with SASS6 and CEP250 proteins (PubMed:25131205). Colocalizes with CEP135 and CEP192 at the centrosomes (PubMed:27185865). Associates with interphase microtubules and mitotic spindles (PubMed:27185865). Colocalizes with centriolar acetylated tubulin (PubMed:25131205). .