- Target
- RN112
- Reactivity
- Human,Mouse,Rat
- Application
- WB,IHC
- MW(Calculated)
- 69kD
- MW(Observed)
- --
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:500-2000;IHC 1:50-300
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- 1 mg/ml
- Clonality
- Polyclonal
- Clone No.
- --
- Immunogen
- Synthesized peptide derived from human RN112 AA range: 377-427
- Sequence
- --
- Specificity
- This antibody detects endogenous levels of RN112 at Human/Mouse/Rat
- Gene Name
- RNF112 BFP ZNF179
- Protein Name
- RN112
- Other Name
- --
- Organism-1
- Human
- Gene ID-1
- 7732
- SwissProt-1
- Q9ULX5
- Organism-2
- Mouse
- Gene ID-2
- 22671
- SwissProt-2
- Q96DY5
- Organism-3
- Rat
- Gene ID-3
- 24916
- SwissProt-3
- O70418
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Membrane ; Multi-pass membrane protein . Membrane ; Peripheral membrane protein . Cytoplasm . Nucleus . Nucleus, nuclear body . Nucleus, nucleoplasm . Endosome . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle . Cell junction, synapse, postsynaptic density . Perikaryon . Cell projection, neuron projection . Predominantly in the nucleus, but some amounts were also found in the cytoplasm. Oxidative stress stimulates its shuttling from the cytoplasm into the nucleus. Recruited to nuclear bodies via its interaction with ZBTB16. Localizes to the cell soma and neuritis and only slightly to the nucleus in the neurons of most brain areas. .