U-Blot® PDPN rabbit pAb

Name: U-Blot® PDPN rabbit pAb
SKU: WP16476
Availability: InStock

$268.00

Size:50μL

SKU: WP16476-50

Catalog No.: WP16476

Specification: 50μL/100μL

Stock: In stock

U-Blot® PDPN rabbit pAb Learn more

Product details Specifications Q & A Education

Background：This gene encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined but it has been proposed as a marker of lung injury. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP16476
SKU: WP16476-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Podoplanin
Reactivity: Human,Mouse,Rat
Application: WB,ELISA,IHC
MW(Calculated): 18kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human PDPN
Sequence: --
Specificity: This antibody detects endogenous levels of PDPN at Human/Mouse/Rat
Gene Name: PDPN GP36 PSEC0003 PSEC0025
Protein Name: Aggrus Glycoprotein 36 Gp36 PA2.26 antigen T1-alpha T1A
Other Name: Podoplanin;Aggrus;Glycoprotein 36;Gp36;PA2.26 antigen;T1-alpha;T1A;
Organism-1: Human
Gene ID-1: 10630
SwissProt-1: Q86YL7
Organism-2: Mouse
Gene ID-2: 14726
SwissProt-2: Q62011
Organism-3: Rat
Gene ID-3: 54320
SwissProt-3: Q64294
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: [Podoplanin]: Membrane ; Single-pass type I membrane protein . Cell projection, lamellipodium membrane ; Single-pass type I membrane protein . Cell projection, filopodium membrane ; Single-pass type I membrane protein . Cell projection, microvillus membrane ; Single-pass type I membrane protein . Cell projection, ruffle membrane ; Single-pass type I membrane protein . Membrane raft . Apical cell membrane . Basolateral cell membrane . Cell projection, invadopodium . Localized to actin-rich microvilli and plasma membrane projections such as filopodia, lamellipodia and ruffles (By similarity). Association to the lipid rafts is required for PDPN-induced epithelial to mesenchymal transition (EMT) (PubMed:21376833). Colocalizes with CD9 in tetraspanin microdomains (PubMed:18541721). Localized at invadopodium adhesion rings in tumor cell. Association to the lipid rafts is essential for PDPN recruitment to invadopodia and ECM degradation (PubMed:25486435). .; [29kDa cytosolic podoplanin intracellular domain]: Cytoplasm, cytosol .