U-Blot® CASC3 rabbit pAb

Name: U-Blot® CASC3 rabbit pAb
SKU: WP16587
Availability: InStock

$268.00

Size:50μL

SKU: WP16587-50

Catalog No.: WP16587

Specification: 50μL/100μL

Stock: In stock

U-Blot® CASC3 rabbit pAb Learn more

Product details Specifications Q & A Education

Background：The product of this gene is a core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated mRNA decay (NMD). The encoded protein binds RNA and interacts with two other EJC core components. It is predominantly located in the cytoplasm, but shuttles into the nucleus where it localizes to nuclear speckles. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP16587
SKU: WP16587-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: CASC3
Reactivity: Human,Mouse,Rat
Application: WB
MW(Calculated): 77kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human CASC3 AA range: 434-484
Sequence: --
Specificity: This antibody detects endogenous levels of CASC3 at Human/Mouse/Rat
Gene Name: CASC3 MLN51
Protein Name: CASC3
Other Name: --
Organism-1: Human
Gene ID-1: 22794
SwissProt-1: O15234
Organism-2: Mouse
Gene ID-2: 192160
SwissProt-2: Q8K3W3
Organism-3: Rat
Gene ID-3: 259170
SwissProt-3: Q8K3X0
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm . Cytoplasm, perinuclear region . Nucleus . Nucleus speckle . Cytoplasm, Stress granule . Cytoplasm, Cytoplasmic ribonucleoprotein granule . Cell projection, dendrite . Shuttles between the nucleus and the cytoplasm in a XPO1/CRM1-dependent manner. Transported to the cytoplasm as part of the exon junction complex (EJC) bound to mRNA (PubMed:15166247). In nuclear speckles, colocalizes with MAGOH. Under stress conditions, colocalizes with FMR1 and TIA1, but not MAGOH and RBM8A EJC core factors, in cytoplasmic stress granules (PubMed:17652158). In the dendrites of hippocampal neurons, localizes to dendritic ribonucleoprotein granules (By similarity). .