U-Blot® RASF5 rabbit pAb

Name: U-Blot® RASF5 rabbit pAb
SKU: WP16603
Availability: InStock

$268.00

Size:50μL

SKU: WP16603-50

Catalog No.: WP16603

Specification: 50μL/100μL

Stock: In stock

U-Blot® RASF5 rabbit pAb Learn more

Product details Specifications Q & A Education

Background：This gene is a member of the Ras association domain family. It functions as a tumor suppressor, and is inactivated in a variety of cancers. The encoded protein localizes to centrosomes and microtubules, and associates with the GTP-activated forms of Ras, Rap1, and several other Ras-like small GTPases. The protein regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or Ras. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP16603
SKU: WP16603-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: RASF5
Reactivity: Human,Mouse,Rat
Application: WB,IF,ELISA,IHC
MW(Calculated): 46kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000;IF/ICC1:50-200;ELISA 1:2000-20000;IHC 1:50-200
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human RASF5 AA range: 234-284
Sequence: --
Specificity: This antibody detects endogenous levels of RASF5 at Human/Mouse/Rat
Gene Name: RASSF5 NORE1 RAPL
Protein Name: RASF5
Other Name: --
Organism-1: Human
Gene ID-1: 83593
SwissProt-1: Q8WWW0
Organism-2: Mouse
Gene ID-2: 54354
SwissProt-2: Q5EBH1
Organism-3: Rat
Gene ID-3: 54355
SwissProt-3: O35141
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm. Cytoplasm, cytoskeleton. Isoform 2 is mainly located in the perinuclear region of unstimulated primary T-cells. Upon stimulation translocates to the leading edge and colocalizes with ITGAL/LFA-1 in the peripheral zone of the immunological synapse. Isoform 2 is localized to growing microtubules in vascular endothelial cells and is dissociated from microtubules by activated RAP1A.