U-Blot® CROCC Polyclonal Antibody

Name: U-Blot® CROCC Polyclonal Antibody
SKU: WP1665
Availability: InStock

$268.00

Size:50μL

SKU: WP1665-50

Catalog No.: WP1665

Specification: 50μL/100μL

Stock: In stock

U-Blot® CROCC Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：function:Major structural component of the ciliary rootlet, a cytoskeletal-like structure in ciliated cells which originates from the basal body at the proximal end of a cilium and extends proximally toward the cell nucleus. Contributes to centrosome cohesion before mitosis.,PTM:Phosphorylated by NEK2 which may regulate its association with centrosomes. Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the rootletin family.,subcellular location:In ciliated cells, associated with ciliary rootlets. In non-ciliated cells, localized between, around and at the proximal ends of the centrioles. Dissociates from the centrioles at the onset of mitosis and reassociates with them at anaphase.,subunit:Homopolymer. Interacts with KLC3, NEK2 and the N-terminus of CEP250.,

Product Overview

Catalog No.: WP1665
SKU: WP1665-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: CROCC
Reactivity: Human,Mouse
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 221kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000;ELISA 1:5000-20000
Form: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human protein . at AA range: 220-300
Sequence: --
Specificity: CROCC Polyclonal Antibody detects endogenous levels of protein.
Gene Name: CROCC KIAA0445
Protein Name: Rootletin (Ciliary rootlet coiled-coil protein)
Other Name: --
Organism-1: Human
Gene ID-1: 9696
SwissProt-1: Q5TZA2
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q8CJ40
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole . Cytoplasm, cytoskeleton, cilium basal body . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . In ciliated cells, associated with ciliary rootlets. In non-ciliated cells, localized between, around and at the proximal ends of the centrioles. Dissociates from the centrioles at the onset of mitosis and reassociates with them at anaphase. .