U-Blot® PUS10 rabbit pAb

Name: U-Blot® PUS10 rabbit pAb
SKU: WP16699
Availability: InStock

$268.00

Size:50μL

SKU: WP16699-50

Catalog No.: WP16699

Specification: 50μL/100μL

Stock: In stock

U-Blot® PUS10 rabbit pAb Learn more

Product details Specifications Q & A Education

Background：Pseudouridination, the isomerization of uridine to pseudouridine, is the most common posttranscriptional nucleotide modification found in RNA and is essential for biologic functions such as spliceosome biogenesis. Pseudouridylate synthases, such as PUS10, catalyze pseudouridination of structural RNAs, including transfer, ribosomal, and splicing RNAs. These enzymes also act as RNA chaperones, facilitating the correct folding and assembly of tRNAs (McCleverty et al., 2007 [PubMed 17900615]).[supplied by OMIM, May 2009],

Product Overview

Catalog No.: WP16699
SKU: WP16699-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: PUS10
Reactivity: Human,Mouse
Application: WB,ELISA,IHC
MW(Calculated): 58kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human PUS10 AA range: 425-475
Sequence: --
Specificity: This antibody detects endogenous levels of PUS10 at Human/Mouse
Gene Name: PUS10 CCDC139 DOBI
Protein Name: PUS10
Other Name: --
Organism-1: Human
Gene ID-1: 150962
SwissProt-1: Q3MIT2
Organism-2: Mouse
Gene ID-2: 74467
SwissProt-2: Q9D3U0
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus . Cytoplasm . Mitochondrion . Localizes mainly in the nucleus (Probable) (PubMed:31819270). tRNA pseudouridylate synthase activity is restricted to the cytoplasm (PubMed:31819270). Translocates from nucleus to mitochondria during TRAIL-induced apoptosis (PubMed:28981101). .