- Target
- RUVB1
- Reactivity
- Human,Mouse,Rat
- Application
- WB
- MW(Calculated)
- 50kD
- MW(Observed)
- --
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:500-2000
- Form
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source
- --
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- 1 mg/ml
- Clonality
- Polyclonal
- Clone No.
- --
- Immunogen
- Synthesized peptide derived from human RUVB1 AA range: 195-245
- Sequence
- --
- Specificity
- This antibody detects endogenous levels of RUVB1 at Human/Mouse/Rat
- Gene Name
- RUVBL1 INO80H NMP238 TIP49 TIP49A
- Protein Name
- RUVB1
- Other Name
- TIP49A
- Organism-1
- Human
- Gene ID-1
- 8607
- SwissProt-1
- Q9Y265
- Organism-2
- Mouse
- Gene ID-2
- 56505
- SwissProt-2
- P60122
- Organism-3
- Rat
- Gene ID-3
- 65137
- SwissProt-3
- P60123
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Nucleus matrix. Nucleus, nucleoplasm. Cytoplasm . Membrane . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Dynein axonemal particle . Mainly localized in the nucleus, associated with nuclear matrix or in the nuclear cytosol, although it is also present in the cytoplasm and associated with the cell membranes. In prophase and prometaphase it is located at the centrosome and the branching microtubule spindles. After mitotic nuclear membrane disintigration it accumulates at the centrosome and sites of tubulin polymerization. As cells pass through metaphase and into telophase it is located close to the centrosome at the early phase of tubulin polymerization. In anaphase it accumulates at the zone of tubule interdigitation. In telophase it is found at polar tubule overlap, and it reappears at the site of chromosomal decondensation in the daughter cells.