U-Blot® 3BP1 Polyclonal Antibody

Name: U-Blot® 3BP1 Polyclonal Antibody
SKU: WP1724
Availability: InStock

$268.00

Size:50μL

SKU: WP1724-50

Catalog No.: WP1724

Specification: 50μL/100μL

Stock: In stock

U-Blot® 3BP1 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：function:Binds differentially to the SH3 domains of certain proteins of signal transduction pathways. This protein binds preferentially to the ABL1 proto-oncogene, SRC and GRB2. Shows GAP activity for Rac-related proteins but not for Rho- or Ras-related proteins. It inhibits PDGF-induced membrane ruffling mediated by Rac.,sequence caution:Translated as Cys.,similarity:Contains 1 BAR domain.,similarity:Contains 1 Rho-GAP domain.,

Product Overview

Catalog No.: WP1724
SKU: WP1724-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: 3BP1
Reactivity: Human,Mouse
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 77kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000;ELISA 1:5000-20000
Form: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human protein . at AA range: 170-250
Sequence: --
Specificity: 3BP1 Polyclonal Antibody detects endogenous levels of protein.
Gene Name: SH3BP1
Protein Name: SH3 domain-binding protein 1 (3BP-1)
Other Name: --
Organism-1: Human
Gene ID-1: 23616
SwissProt-1: Q9Y3L3
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: P55194
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cell projection . Cell junction, tight junction . Cell junction, adherens junction . Cell projection, phagocytic cup . Nucleus . Cytoplasm, cytosol . Localizes at the leading edge of migrating cells (PubMed:21658605, PubMed:24841563). Accumulation at forming phagocytic cups is PI3 kinase/PI3K-dependent and is specific for sites of large particles engagement and their phosphatidylinositol 3,4,5-triphosphate membrane content (PubMed:26465210). .