U-Blot® DREB rabbit pAb

Name: U-Blot® DREB rabbit pAb
SKU: WP17531
Availability: InStock

$268.00

Size:50μL

SKU: WP17531-50

Catalog No.: WP17531

Specification: 50μL/100μL

Stock: In stock

U-Blot® DREB rabbit pAb Learn more

Product details Specifications Q & A Education

Background：The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP17531
SKU: WP17531-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: DREB
Reactivity: Human,Mouse,Rat
Application: WB
MW(Calculated): 71kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human DREB AA range: 484-534
Sequence: --
Specificity: This antibody detects endogenous levels of DREB at Human/Mouse/Rat
Gene Name: DBN1 D0S117E
Protein Name: DREB
Other Name: --
Organism-1: Human
Gene ID-1: 1627
SwissProt-1: Q16643
Organism-2: Mouse
Gene ID-2: 56320
SwissProt-2: Q9QXS6
Organism-3: Rat
Gene ID-3: 81653
SwissProt-3: Q07266
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm . Cell projection, dendrite . Cytoplasm, cell cortex . Cell junction . Cell projection, growth cone . In the absence of antigen, evenly distributed throughout subcortical regions of the T-cell membrane and cytoplasm (PubMed:20215400). In the presence of antigen, distributes to the immunological synapse forming at the T-cell-APC contact area, where it localizes at the peripheral and distal supramolecular activation clusters (SMAC) (PubMed:20215400). Colocalized with RUFY3 and F-actin at the transitional domain of the axonal growth cone (By similarity). .