U-Blot® Cdk9 rabbit pAb

Name: U-Blot® Cdk9 rabbit pAb
SKU: WP17686
Availability: InStock

$268.00

Size:50μL

SKU: WP17686-50

Catalog No.: WP17686

Specification: 50μL/100μL

Stock: In stock

U-Blot® Cdk9 rabbit pAb Learn more

Product details Specifications Q & A Education

Background：cyclin dependent kinase 9(CDK9) Homo sapiens The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP17686
SKU: WP17686-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: Cdk9
Reactivity: Human,Rat,Mouse,
Application: WB,ELISA
MW(Calculated): 41kD
MW(Observed): --
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:1000-2000;ELISA 1:5000-20000
Form: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human Cdk9
Sequence: --
Specificity: This antibody detects endogenous levels of Human Cdk9
Gene Name: CDK9 CDC2L4 TAK
Protein Name: Cdk9
Other Name: Cyclin-dependent kinase 9;EC 2.7.11.23;C-2K;Cell division cycle 2-like protein kinase 4;Cell division protein kinase 9;Serine/threonine-protein kinase PITALRE;Tat-associated kinase complex catalytic subunit;
Organism-1: Human
Gene ID-1: 1025
SwissProt-1: P50750
Organism-2: Mouse
Gene ID-2: 107951
SwissProt-2: Q99J95
Organism-3: Rat
Gene ID-3: 362110
SwissProt-3: Q641Z4
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus. Cytoplasm. Nucleus, PML body. Accumulates on chromatin in response to replication stress. Complexed with CCNT1 in nuclear speckles, but uncomplexed form in the cytoplasm. The translocation from nucleus to cytoplasm is XPO1/CRM1-dependent. Associates with PML body when acetylated.