U-Blot® SNX5 Polyclonal Antibody

Name: U-Blot® SNX5 Polyclonal Antibody
SKU: WP1776
Availability: InStock

$268.00

Size:50μL

SKU: WP1776-50

Catalog No.: WP1776

Specification: 50μL/100μL

Stock: In stock

U-Blot® SNX5 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein functions in endosomal sorting, the phosphoinositide-signaling pathway, and macropinocytosis. This gene may play a role in the tumorigenesis of papillary thyroid carcinoma. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2013],

Product Overview

Catalog No.: WP1776
SKU: WP1776-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: SNX5
Reactivity: Human,Rat,Mouse
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 47kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000;ELISA 1:5000-20000
Form: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from part region of human protein
Sequence: --
Specificity: SNX5 Polyclonal Antibody detects endogenous levels of protein.
Gene Name: SNX5
Protein Name: Sorting nexin-5
Other Name: --
Organism-1: Human
Gene ID-1: 27131
SwissProt-1: Q9Y5X3
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q9D8U8
Organism-3: Rat
Gene ID-3: --
SwissProt-3: B1H267
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Endosome . Early endosome . Early endosome membrane ; Peripheral membrane protein; Cytoplasmic side. Cell membrane ; Peripheral membrane protein; Cytoplasmic side . Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm. Cell projection, phagocytic cup. Cell projection, ruffle. Recruited to the plasma membrane after EGF stimulation, which leads to increased levels of phosphatidylinositol 3,4-bisphosphate (PdtIns(3,4)P2) (PubMed:15561769). Detected on macropinosomes (PubMed:16968745, PubMed:21048941). Targeted to membrane ruffles in response to EGFR stimulation. .