- Target
- PIEZ1
- Reactivity
- Human,Mouse,Rat
- Application
- IHC,WB
- MW(Calculated)
- 277kD
- MW(Observed)
- --
- Host Species
- Rabbit
- Isotype
- IgG
- Conjugate/Modification
- Unmodified
- Modification site
- --
- Recommended Dilution Ratio
- WB 1:500-2000;IHC 1:50-200
- Form
- PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
- Source
- --
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Purity
- --
- storageCondition
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Concentration
- 1 mg/ml
- Clonality
- Polyclonal
- Clone No.
- --
- Immunogen
- Synthesized peptide derived from human C-ternal PIEZ1
- Sequence
- --
- Specificity
- This antibody detects endogenous levels of PIEZ1 at Human, Mouse,Rat
- Gene Name
- PIEZO1 FAM38A KIAA0233
- Protein Name
- Piezo-type mechanosensitive ion channel component 1 (Membrane protein induced by beta-amyloid treatment) (Mib) (Protein FAM38A)
- Other Name
- Piezo-type mechanosensitive ion channel component 1;Membrane protein induced by beta-amyloid treatment;Mib;Protein FAM38A;
- Organism-1
- Human
- Gene ID-1
- 9780
- SwissProt-1
- Q92508
- Organism-2
- Mouse
- Gene ID-2
- --
- SwissProt-2
- E2JF22
- Organism-3
- Rat
- Gene ID-3
- 361430
- SwissProt-3
- Q0KL00
- Organism-4
- --
- gene ID-4
- --
- SwissProt-4
- --
- Cellular Localization
- Endoplasmic reticulum membrane ; Multi-pass membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane . Cell membrane ; Multi-pass membrane protein . Cell projection, lamellipodium membrane . Cell membrane ; Multi-pass membrane protein. In erythrocytes, located in the plasma membrane (PubMed:22529292, PubMed:23479567). Accumulates at the leading apical lamellipodia of endothelial cells in response to shear stress (PubMed:25119035). Colocalizes with F-actin and MYH9 at the actomyosin cortex in myoblasts. .