U-Blot® B2L10 Polyclonal Antibody

Name: U-Blot® B2L10 Polyclonal Antibody
SKU: WP1975
Availability: InStock

$268.00

Size:50μL

SKU: WP1975-50

Catalog No.: WP1975

Specification: 50μL/100μL

Stock: In stock

U-Blot® B2L10 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP1975
SKU: WP1975-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: B2L10
Reactivity: Human,Rat,Mouse,
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 21kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000;ELISA 1:5000-20000
Form: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human protein . at AA range: 70-150
Sequence: --
Specificity: B2L10 Polyclonal Antibody detects endogenous levels of protein.
Gene Name: BCL2L10 BCLB
Protein Name: Bcl-2-like protein 10 (Bcl2-L-10) (Anti-apoptotic protein NrH) (Apoptosis regulator Bcl-B)
Other Name: --
Organism-1: Human
Gene ID-1: 10017
SwissProt-1: Q9HD36
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q9Z0F3
Organism-3: Rat
Gene ID-3: --
SwissProt-3: Q99M66
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Mitochondrion . Nucleus membrane . Endoplasmic reticulum . Cytoplasm, cytoskeleton, spindle . Localizes to mitochondria-associated endoplasmic reticulum membranes (MAMs) (PubMed:27995898). Localization to MAMs is greatly reduced under apoptotic stress conditions (PubMed:27995898). .