U-Blot® LRRK2 Polyclonal Antibody

Name: U-Blot® LRRK2 Polyclonal Antibody
SKU: WP2279
Availability: InStock

$268.00

Size:50μL

SKU: WP2279-50

Catalog No.: WP2279

Specification: 50μL/100μL

Stock: In stock

U-Blot® LRRK2 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP2279
SKU: WP2279-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: LRRK2
Reactivity: Human,Mouse
Application: IHC,IF
MW(Calculated): --
MW(Observed): 277kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: IHC 1:50-300;IF 1:50-200
Form: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from part region of human protein
Sequence: --
Specificity: LRRK2 Polyclonal Antibody detects endogenous levels of protein.
Gene Name: LRRK2 PARK8
Protein Name: Leucine-rich repeat serine/threonine-protein kinase 2 (Dardarin)
Other Name: --
Organism-1: Human
Gene ID-1: 120892
SwissProt-1: Q5S007
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q5S006
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasmic vesicle . Perikaryon . Golgi apparatus membrane ; Peripheral membrane protein . Cell projection, axon . Cell projection, dendrite . Endoplasmic reticulum membrane ; Peripheral membrane protein . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane . Endosome . Lysosome . Mitochondrion outer membrane ; Peripheral membrane protein . Colocalized with RAB29 along tubular structures emerging from Golgi apparatus (PubMed:23395371). Localizes to endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER) (PubMed:25201882). .