U-Blot® IL18 Polyclonal Antibody

Name: U-Blot® IL18 Polyclonal Antibody
SKU: WP2329
Availability: InStock

$268.00

Size:50μL

SKU: WP2329-50

Catalog No.: WP2329

Specification: 50μL/100μL

Stock: In stock

U-Blot® IL18 Polyclonal Antibody Learn more

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Background：The protein encoded by this gene is a proinflammatory cytokine that augments natural killer cell activity in spleen cells, and stimulates interferon gamma production in T-helper type I cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2011],

Product Overview

Catalog No.: WP2329
SKU: WP2329-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: IL18
Reactivity: Human,Rat,Mouse
Application: WB IF,ELISA
MW(Calculated): --
MW(Observed): 21kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000;IF 1:100-300;ELISA 1:5000-20000;Not yet tested in other applications.
Form: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from part region of human protein
Sequence: --
Specificity: IL18 Polyclonal Antibody detects endogenous levels of protein.
Gene Name: IL18 IGIF IL1F4
Protein Name: Interleukin-18 (IL-18) (Iboctadekin) (Interferon gamma-inducing factor) (IFN-gamma-inducing factor) (Interleukin-1 gamma) (IL-1 gamma)
Other Name: --
Organism-1: Human
Gene ID-1: 3606
SwissProt-1: Q14116
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: P70380
Organism-3: Rat
Gene ID-3: --
SwissProt-3: P97636
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm . Secreted . The precursor is cytosolic (PubMed:33883744). In response to inflammasome-activating signals, cleaved and secreted (PubMed:33883744). Mature form is secreted and released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore (PubMed:33883744). In contrast, the precursor form is not released, due to the presence of an acidic region that is proteolytically removed by CASP1 during maturation (PubMed:33883744). The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10 (PubMed:32272059). .