U-Blot® PINK1 Polyclonal Antibody

Name: U-Blot® PINK1 Polyclonal Antibody
SKU: WP2437
Availability: InStock

$268.00

Size:50μL

SKU: WP2437-50

Catalog No.: WP2437

Specification: 50μL/100μL

Stock: In stock

U-Blot® PINK1 Polyclonal Antibody Learn more

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Background：This gene encodes a serine/threonine protein kinase that localizes to mitochondria. It is thought to protect cells from stress-induced mitochondrial dysfunction. Mutations in this gene cause one form of autosomal recessive early-onset Parkinson disease. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP2437
SKU: WP2437-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: PINK1
Reactivity: Human,Mouse,Rat
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 63kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000;ELISA 1:5000-20000
Form: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from part region of human protein
Sequence: --
Specificity: PINK1 Polyclonal Antibody detects endogenous levels of protein.
Gene Name: PINK1
Protein Name: Serine/threonine-protein kinase PINK1, mitochondrial (BRPK) (PTEN-induced putative kinase protein 1)
Other Name: --
Organism-1: Human
Gene ID-1: 65018
SwissProt-1: Q9BXM7
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q99MQ3
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Mitochondrion outer membrane ; Single-pass membrane protein . Mitochondrion inner membrane ; Single-pass membrane protein . Cytoplasm, cytosol . Localizes mostly in mitochondrion and the two smaller proteolytic processed fragments localize mainly in cytosol (PubMed:19229105). When mitochondria lose mitochondrial membrane potential following damage, PINK1 import is arrested, which induces its accumulation in the outer mitochondrial membrane, where it acquires kinase activity (PubMed:18957282). .