U-Blot® LOXL2 Polyclonal Antibody

Name: U-Blot® LOXL2 Polyclonal Antibody
SKU: WP2524
Availability: InStock

$268.00

Size:50μL

SKU: WP2524-50

Catalog No.: WP2524

Specification: 50μL/100μL

Stock: In stock

U-Blot® LOXL2 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP2524
SKU: WP2524-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: LOXL2
Reactivity: Human,Rat,Mouse
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 85kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000;ELISA 1:5000-20000
Form: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from part region of human protein
Sequence: --
Specificity: LOXL2 Polyclonal Antibody detects endogenous levels of protein.
Gene Name: LOXL2
Protein Name: Lysyl oxidase homolog 2 (Lysyl oxidase-like protein 2) (Lysyl oxidase-related protein 2) (Lysyl oxidase-related protein WS9-14)
Other Name: --
Organism-1: Human
Gene ID-1: 4017
SwissProt-1: Q9Y4K0
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: P58022
Organism-3: Rat
Gene ID-3: --
SwissProt-3: B5DF27
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Secreted, extracellular space, extracellular matrix, basement membrane . Nucleus . Chromosome . Endoplasmic reticulum . Associated with chromatin (PubMed:27735137). It is unclear how LOXL2 is nuclear as it contains a signal sequence and has been shown to be secreted (PubMed:23319596). However, a number of reports confirm its intracellular location and its key role in transcription regulation (PubMed:22204712, PubMed:22483618). .