U-Blot® LN28B Polyclonal Antibody

Name: U-Blot® LN28B Polyclonal Antibody
SKU: WP2695
Availability: InStock

$268.00

Size:50μL

SKU: WP2695-50

Catalog No.: WP2695

Specification: 50μL/100μL

Stock: In stock

U-Blot® LN28B Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：The protein encoded by this gene belongs to the lin-28 family, which is characterized by the presence of a cold-shock domain and a pair of CCHC zinc finger domains. This gene is highly expressed in testis, fetal liver, placenta, and in primary human tumors and cancer cell lines. It is negatively regulated by microRNAs that target sites in the 3' UTR, and overexpression of this gene in primary tumors is linked to the repression of let-7 family of microRNAs and derepression of let-7 targets, which facilitates cellular transformation. [provided by RefSeq, Jun 2012],

Product Overview

Catalog No.: WP2695
SKU: WP2695-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: LN28B
Reactivity: Human,Mouse
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 27kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000;ELISA 1:5000-20000
Form: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human protein . at AA range: 60-140
Sequence: --
Specificity: LN28B Polyclonal Antibody detects endogenous levels of protein.
Gene Name: LIN28B CSDD2
Protein Name: Protein lin-28 homolog B (Lin-28B)
Other Name: --
Organism-1: Human
Gene ID-1: 389421
SwissProt-1: Q6ZN17
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q45KJ6
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus. Nucleus, nucleolus . Cytoplasm . Predominantly nucleolar (PubMed:22118463). In Huh7 cells, predominantly cytoplasmic, with only a subset of cells exhibiting strong nuclear staining; however, the specificity of the polyclonal antibody used in these experiments has not been not documented (PubMed:16971064). .