U-Blot® HBEGF Polyclonal Antibody

Name: U-Blot® HBEGF Polyclonal Antibody
SKU: WP2708
Availability: InStock

$268.00

Size:50μL

SKU: WP2708-50

Catalog No.: WP2708

Specification: 50μL/100μL

Stock: In stock

U-Blot® HBEGF Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：function:May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts and smooth muscle but not endothelial cells. It is able to bind EGF receptors with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.,PTM:O-linked glycan attachment sites were determined by Edman degradation, O-glycanase digest suggests mucin-type glycosylation (done in HB-EGF purified from histiocytic lymphoma cell line U-937).,PTM:Several N-termini have been identified by direct sequencing. The forms with N-termini 63, 73 and 74 have been tested and found to be biologically active.,similarity:Contains 1 EGF-like domain.,subcellular location:Mature HB-EGF is released into the extracellular space and probably binds to a receptor.,

Product Overview

Catalog No.: WP2708
SKU: WP2708-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: HBEGF
Reactivity: Human,Rat,Mouse
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 22kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000;ELISA 1:5000-20000
Form: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human protein . at AA range: 130-210
Sequence: --
Specificity: HBEGF Polyclonal Antibody detects endogenous levels of protein.
Gene Name: HBEGF DTR DTS HEGFL
Protein Name: Proheparin-binding EGF-like growth factor [Cleaved into: Heparin-binding EGF-like growth factor (HB-EGF) (HBEGF) (Diphtheria toxin receptor) (DT-R)]
Other Name: --
Organism-1: Human
Gene ID-1: 1839
SwissProt-1: Q99075
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q06186
Organism-3: Rat
Gene ID-3: --
SwissProt-3: Q06175
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: [Heparin-binding EGF-like growth factor]: Secreted, extracellular space. Mature HB-EGF is released into the extracellular space and probably binds to a receptor.; [Proheparin-binding EGF-like growth factor]: Cell membrane; Single-pass type I membrane protein.