U-Blot® CLN3 Polyclonal Antibody

Name: U-Blot® CLN3 Polyclonal Antibody
SKU: WP2878
Availability: InStock

$268.00

Size:50μL

SKU: WP2878-50

Catalog No.: WP2878

Specification: 50μL/100μL

Stock: In stock

U-Blot® CLN3 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes a protein that is involved in lysosomal function. Mutations in this, as well as other neuronal ceroid-lipofuscinosis (CLN) genes, cause neurodegenerative diseases commonly known as Batten disease or collectively known as neuronal ceroid lipofuscinoses (NCLs). Many alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008],

Product Overview

Catalog No.: WP2878
SKU: WP2878-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: CLN3
Reactivity: Human,Mouse
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 48kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000;ELISA 1:5000-20000
Form: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human protein . at AA range: 221-270
Sequence: --
Specificity: CLN3 Polyclonal Antibody detects endogenous levels of protein.
Gene Name: CLN3 BTS
Protein Name: Battenin (Batten disease protein) (Protein CLN3)
Other Name: --
Organism-1: Human
Gene ID-1: 1201
SwissProt-1: Q13286
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q61124
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Lysosome membrane ; Multi-pass membrane protein . Late endosome . Lysosome . Golgi apparatus . Golgi apparatus membrane . Golgi apparatus, Golgi stack . Golgi apparatus, trans-Golgi network . Cell membrane . Recycling endosome . Membrane raft . Membrane, caveola . Early endosome membrane . Cell junction, synapse, synaptosome . Late endosome membrane . Cytoplasmic vesicle, autophagosome . CLN3 is not present in late endosomes/lysosomes in fibroblasts and neurons (PubMed:15240864). Trafficks from cell membrane to Golgi via endosomes (PubMed:15240864). Osmotic stress changes the subcellular localization of CLN3 (PubMed:23840424). Trafficks to intracellular compartments via the plasma membranet through AP3M1-dependent mechanisms (PubMed:14644441). Excluded from the synaptic vesicles (By similarity). .