U-Blot® SARM1 Polyclonal Antibody

Name: U-Blot® SARM1 Polyclonal Antibody
SKU: WP2879
Availability: InStock

$268.00

Size:50μL

SKU: WP2879-50

Catalog No.: WP2879

Specification: 50μL/100μL

Stock: In stock

U-Blot® SARM1 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：caution:Was initially reported to contain ARM repeats (PubMed:11386760). Such repeats are however not predicted by any detection method.,function:Involved in innate immnune response. Acts as a negative regulator of TICAM1/TRIF-dependent Toll-like receptor signaling by inhibiting induction of TLR3- and TLR4-dependent genes. Specifically blocks TICAM1/TRIF-dependent transcription-factor activation and gene induction, without affecting the MYD88-dependent pathway or non-TLR signaling. Negative regulator of NF-kappa-B and IRF activation.,similarity:Contains 1 TIR domain.,similarity:Contains 2 SAM (sterile alpha motif) domains.,subunit:Interacts with TICAM1/TRIF and thereby interferes with TICAM1/TRIF function.,tissue specificity:Predominantly expressed in kidney and liver. Expressed at lower level in placenta.,

Product Overview

Catalog No.: WP2879
SKU: WP2879-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: SARM1
Reactivity: Human,Mouse
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 79kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000;ELISA 1:5000-20000
Form: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human protein . at AA range: 281-330
Sequence: --
Specificity: SARM1 Polyclonal Antibody detects endogenous levels of protein.
Gene Name: SARM1 KIAA0524 SAMD2 SARM
Protein Name: Sterile alpha and TIR motif-containing protein 1 (Sterile alpha and Armadillo repeat protein) (Sterile alpha motif domain-containing protein 2) (SAM domain-containing protein 2) (Tir-1 homolog)
Other Name: --
Organism-1: Human
Gene ID-1: 23098
SwissProt-1: Q6SZW1
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q6PDS3
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm . Cell projection, axon . Cell projection, dendrite . Cell junction, synapse . Mitochondrion . Associated with microtubules. .