U-Blot® APTX Polyclonal Antibody

Name: U-Blot® APTX Polyclonal Antibody
SKU: WP2886
Availability: InStock

$268.00

Size:50μL

SKU: WP2886-50

Catalog No.: WP2886

Specification: 50μL/100μL

Stock: In stock

U-Blot® APTX Polyclonal Antibody Learn more

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Background：aprataxin(APTX) Homo sapiens This gene encodes a member of the histidine triad (HIT) superfamily. The encoded protein may play a role in single-stranded DNA repair through its nucleotide-binding activity and its diadenosine polyphosphate hydrolase activity. Mutations in this gene have been associated with ataxia-ocular apraxia. Alternatively spliced transcript variants have been identified for this gene.[provided by RefSeq, Aug 2010],

Product Overview

Catalog No.: WP2886
SKU: WP2886-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: APTX
Reactivity: Human,Mouse,Rat
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 39kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000;ELISA 1:5000-20000
Form: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from human protein . at AA range: 11-60
Sequence: --
Specificity: APTX Polyclonal Antibody detects endogenous levels of protein.
Gene Name: APTX AXA1
Protein Name: Aprataxin (Forkhead-associated domain histidine triad-like protein) (FHA-HIT)
Other Name: --
Organism-1: Human
Gene ID-1: 54840
SwissProt-1: Q7Z2E3
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: Q7TQC5
Organism-3: Rat
Gene ID-3: --
SwissProt-3: Q8K4H4
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Nucleus, nucleoplasm . Nucleus, nucleolus . Upon genotoxic stress, colocalizes with XRCC1 at sites of DNA damage (PubMed:15380105). Colocalizes with MDC1 at sites of DNA double-strand breaks (PubMed:20008512). Interaction with NCL is required for nucleolar localization (PubMed:16777843). .; [Isoform 12]: Cytoplasm .