U-Blot® PABP1 Polyclonal Antibody

Name: U-Blot® PABP1 Polyclonal Antibody
SKU: WP3193
Availability: InStock

$268.00

Size:50μL

SKU: WP3193-50

Catalog No.: WP3193

Specification: 50μL/100μL

Stock: In stock

U-Blot® PABP1 Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：This gene encodes a poly(A) binding protein. The protein shuttles between the nucleus and cytoplasm and binds to the 3' poly(A) tail of eukaryotic messenger RNAs via RNA-recognition motifs. The binding of this protein to poly(A) promotes ribosome recruitment and translation initiation; it is also required for poly(A) shortening which is the first step in mRNA decay. The gene is part of a small gene family including three protein-coding genes and several pseudogenes.[provided by RefSeq, Aug 2010],

Product Overview

Catalog No.: WP3193
SKU: WP3193-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: PABP1
Reactivity: Human,Rat,Mouse,
Application: WB,ELISA
MW(Calculated): --
MW(Observed): 69kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: WB 1:500-2000;ELISA 1:5000-20000
Form: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from part region of human protein AA range: 212-262
Sequence: --
Specificity: PABP1 Polyclonal Antibody detects endogenous levels of protein.
Gene Name: PABPC1 PAB1 PABP1 PABPC2
Protein Name: Polyadenylate-binding protein 1 (PABP-1) (Poly(A)-binding protein 1)
Other Name: --
Organism-1: Human
Gene ID-1: 26986
SwissProt-1: P11940
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: P29341
Organism-3: Rat
Gene ID-3: --
SwissProt-3: Q9EPH8
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasm . Cytoplasm, Stress granule . Nucleus . Cell projection, lamellipodium . Localized in cytoplasmic mRNP granules containing untranslated mRNAs (PubMed:17289661). Shuttles between the cytoplasm and the nucleus (PubMed:9582337). During stress and in the absence of DDX3X, localizes to the nucleus (PubMed:21883093). At the leading edge of migrating fibroblasts, colocalizes with DDX3X (PubMed:28733330). Relocalizes to cytoplasmic stress granules upon cellular stress where it colocalizes with ENDOV (PubMed:27573237). In case of HRSV infection, localizes in cytoplasmic inclusion bodies substructures called inclusion bodies associated granules (IBAGs) (PubMed:31649314). .