U-Blot® FILA Polyclonal Antibody

Name: U-Blot® FILA Polyclonal Antibody
SKU: WP3259
Availability: InStock

$268.00

Size:50μL

SKU: WP3259-50

Catalog No.: WP3259

Specification: 50μL/100μL

Stock: In stock

U-Blot® FILA Polyclonal Antibody Learn more

Product details Specifications Q & A Education

Background：The protein encoded by this gene is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Mutations in this gene are associated with ichthyosis vulgaris.[provided by RefSeq, Dec 2009],

Product Overview

Catalog No.: WP3259
SKU: WP3259-50
Category: Polyclonal antibodies
Product Type: Other
Size: 50μL/100μL
Stock Status: In stock
Available Stock: 20
Minimum Order Quantity: 1

Storage & Compliance

Storage: -15°C to -25°C/1 year(Do not lower than -25°C)
Research Use Only: Yes

Additional Specifications

Target: FILA
Reactivity: Human,Mouse
Application: IHC,IF
MW(Calculated): --
MW(Observed): 446kD
Host Species: Rabbit
Isotype: IgG
Conjugate/Modification: Unmodified
Modification site: --
Recommended Dilution Ratio: IHC 1:50-300;IF 1:50-200
Form: PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Source: --
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity: --
storageCondition: -15°C to -25°C/1 year(Do not lower than -25°C)
Concentration: 1 mg/ml
Clonality: Polyclonal
Clone No.: --
Immunogen: Synthesized peptide derived from part region of human protein
Sequence: --
Specificity: FILA Polyclonal Antibody detects endogenous levels of protein.
Gene Name: FLG
Protein Name: Filaggrin
Other Name: --
Organism-1: Human
Gene ID-1: 2312
SwissProt-1: P20930
Organism-2: Mouse
Gene ID-2: --
SwissProt-2: P11088
Organism-3: --
Gene ID-3: --
SwissProt-3: --
Organism-4: --
gene ID-4: --
SwissProt-4: --
Cellular Localization: Cytoplasmic granule . In the stratum granulosum of the epidermis, localized within keratohyalin granules (PubMed:1429717). In granular keratinocytes and in lower corneocytes, colocalizes with calpain-1/CAPN1 (PubMed:21531719). .